Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q7JJ
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| Former ID |
DIB009941
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| Drug Name |
NA-808
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| Synonyms |
HCV replication inhibitors, Chugai; Hepatitis C virus replication inhibitors, Chugai; NA-255; SPT inhibitor (injection, HCV infection), Roche/Chugai; SPT inhibitor (injection, hepatitis C virus infection), Roche/Chugai; Serine palmitoyltransferase inhibitor (injection, HCV infection), Roche/Chugai; Serine palmitoyltransferase inhibitor (injection, hepatitis C virus infection), Roche/Chugai
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| Indication | Hepatitis C virus infection [ICD-11: 1E51.1; ICD-10: B18.2] | Preclinical | [1] | |
| Company |
Chugai Pharmaceutical Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C34H48O9
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| Canonical SMILES |
CCCCCCCC(=O)CCCCCCC=CC(C(CC1=CC=C(C=C1)OCC#CC)C(=O)O)C(CC(=O)O)(C(=O)O)O
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| InChI |
1S/C34H48O9/c1-3-5-7-10-13-16-27(35)17-14-11-8-9-12-15-18-30(34(42,33(40)41)25-31(36)37)29(32(38)39)24-26-19-21-28(22-20-26)43-23-6-4-2/h15,18-22,29-30,42H,3,5,7-14,16-17,23-25H2,1-2H3,(H,36,37)(H,38,39)(H,40,41)/b18-15+/t29-,30-,34-/m0/s1
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| InChIKey |
XQPJMZTYCIBZTB-UIWDEBCHSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Serine palmitoyltransferase (SPTC) | Target Info | Modulator | [2] |
| References | Top | |||
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| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023649) | |||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
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