Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q7IX
|
|||
| Former ID |
DIB000209
|
|||
| Drug Name |
PF-06342674
|
|||
| Indication | Type-1 diabetes [ICD-11: 5A10; ICD-9: 250] | Phase 1 | [1] | |
| Type-2 diabetes [ICD-11: 5A11; ICD-9: 250] | Phase 1 | [2] | ||
| Company |
Pfizer
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin 7 receptor alpha (IL7R) | Target Info | Antagonist | [2], [3] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| FoxO signaling pathway | ||||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| Primary immunodeficiency | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| IL4 Signaling Pathway | ||||
| TNFalpha Signaling Pathway | ||||
| Leptin Signaling Pathway | ||||
| Reactome | Interleukin-7 signaling | |||
| WikiPathways | Apoptosis-related network due to altered Notch3 in ovarian cancer | |||
| Interleukin-7 signaling | ||||
| TSLP Signaling Pathway | ||||
| IL-7 Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037233) | |||
| REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 3 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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