Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q4EG
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| Former ID |
DIB020571
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| Drug Name |
NQN-1
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| Synonyms |
PPM-18; NSC 73233
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C17H11NO3
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| Canonical SMILES |
C1=CC=C(C=C1)C(=O)NC2=CC(=O)C3=CC=CC=C3C2=O
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| InChI |
1S/C17H11NO3/c19-15-10-14(16(20)13-9-5-4-8-12(13)15)18-17(21)11-6-2-1-3-7-11/h1-10H,(H,18,21)
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| InChIKey |
BIVQBWSIGJFXLF-UHFFFAOYSA-N
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| CAS Number |
CAS 65240-86-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
115594, 4500646, 8153001, 11451488, 14775168, 26759386, 29223961, 47515442, 51970674, 57322501, 89855681, 103831257, 104307700, 117586884, 121366145, 125252395, 125728695, 137099533, 142554898, 160644540, 163137445, 163687467, 170475398, 174499964, 178103637, 196376604, 226531968, 244011748, 252468996, 252656708
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histone deacetylase 6 (HDAC6) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alcoholism | |||
| Viral carcinogenesis | ||||
| Pathway Interaction Database | Signaling events mediated by HDAC Class II | |||
| Signaling events mediated by HDAC Class I | ||||
| Reactome | NOTCH1 Intracellular Domain Regulates Transcription | |||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | ||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | ||||
| Assembly of the primary cilium | ||||
| WikiPathways | Ectoderm Differentiation | |||
| Neural Crest Differentiation | ||||
| Cell Cycle | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A novel class of small molecule inhibitors of HDAC6. ACS Chem Biol. 2012 Feb 17;7(2):331-9. | |||
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