Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q2HM
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| Former ID |
DIB010791
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| Drug Name |
EDD7H9
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| Synonyms |
Anti S1P3 antibody (breast cancer), Expression Drug Designs; Anti-GPCR Abs (cancer), Expression Drug Designs; G-protein-coupled receptor inhibitor antibodies (breast cancer), Expression Drug Designs
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| Drug Type |
Antibody
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| Indication | Breast cancer [ICD-11: 2C60-2C65; ICD-10: C50, C79.51] | Preclinical | [1] | |
| Company |
Expression Drug Designs
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target Info | . | [2] |
| KEGG Pathway | Sphingolipid signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | S1P3 pathway | |||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| Reactome | G alpha (i) signalling events | |||
| Lysosphingolipid and LPA receptors | ||||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Opportunities for therapeutic antibodies directed at G-protein-coupled receptors. Nat Rev Drug Discov. 2017 Sep;16(9):787-810. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 277). | |||
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