Drug Information
Drug General Information | Top | |||
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Drug ID |
D0PK3W
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Former ID |
DIB014758
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Drug Name |
Lotilibcin
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Synonyms |
Lotilibcin; JA-002; JA-003; WAP-8294A2; Acne therapy (dermatological formulation), Janus; Lotilibcin (injectable), aRigen; MRSA infection therapy (gel), Janus; S aureus infection therapy (gel), Janus; Lotilibcin (cream, acne), Janus; Lotilibcin (dermatological cream, acne), aRigen; Lotilibcin (gel, Staphycoccus infection), aRigen; Lotilibcin (gel, skin infections), Janus; WAP-8294A2 (injectable), aRigen; WAP-8294A2 (cream, acne), Janus; WAP-8294A2 (dermatological cream, acne), aRigen; WAP-8294A2 (gel, MRSA), aRigen; WAP-8294A2 (gel, skin infections), Janus
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Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Phase 1 | [1] | |
Company |
Wakamoto Pharmaceutical Co Ltd
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Structure |
Download2D MOL |
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Formula |
C73H111N17O21
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Canonical SMILES |
CC(C)CCCC1CC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N(C(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)O1)C(C)C)C)CCCN)CC2=CNC3=CC=CC=C32)CC(=O)N)CCC(=O)O)CCCN)CC(C)C)CC4=CC=CC=C4)C)CO)C(C(=O)N)O)CO
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InChI |
1S/C73H111N17O21/c1-38(2)17-14-20-43-32-56(94)80-53(37-92)69(106)88-59(61(98)62(77)99)71(108)87-52(36-91)63(100)79-35-57(95)89(7)54(30-41-18-10-9-11-19-41)70(107)86-49(29-39(3)4)66(103)81-46(23-15-27-74)64(101)82-47(25-26-58(96)97)65(102)85-51(33-55(76)93)68(105)84-50(31-42-34-78-45-22-13-12-21-44(42)45)67(104)83-48(24-16-28-75)72(109)90(8)60(40(5)6)73(110)111-43/h9-13,18-19,21-22,34,38-40,43,46-54,59-61,78,91-92,98H,14-17,20,23-33,35-37,74-75H2,1-8H3,(H2,76,93)(H2,77,99)(H,79,100)(H,80,94)(H,81,103)(H,82,101)(H,83,104)(H,84,105)(H,85,102)(H,86,107)(H,87,108)(H,88,106)(H,96,97)/t43-,46-,47+,48-,49+,50-,51-,52+,53+,54-,59-,60+,61-/m1/s1
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InChIKey |
LEKBQPKGXGFBAN-MMXTXZKOSA-N
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CAS Number |
169148-84-9
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Bacterial Cell membrane (Bact CM) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011609) | |||
REF 2 | Bioactive natural products from Lysobacter. Nat Prod Rep. 2012 November 8; 29(11): 1277-1287. |
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