Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0PH1G
|
|||
| Former ID |
DNC010502
|
|||
| Drug Name |
3-[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]-1-propanol
|
|||
| Synonyms |
CHEMBL598399; SCHEMBL3822518; 3-[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]-1-propanol; ACOYOVQVLSTOMH-UHFFFAOYSA-N; ZINC34123980; BDBM50307226; AKOS027324260; 1-p-Cyanophenylmethyl-5-(3-hydroxypropyl)-1H-imidazole; 1-(p-cyanophenylmethyl)-5-(3-hydroxypropyl)-1H-imidazole; 1-(p-Cyanophenylmethyl)-5-(3-hydroxypropyl) -1H-imidazole
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C14H15N3O
|
|||
| Canonical SMILES |
C1=CC(=CC=C1CN2C=NC=C2CCCO)C#N
|
|||
| InChI |
1S/C14H15N3O/c15-8-12-3-5-13(6-4-12)10-17-11-16-9-14(17)2-1-7-18/h3-6,9,11,18H,1-2,7,10H2
|
|||
| InChIKey |
ACOYOVQVLSTOMH-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.