Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0PG8M
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| Former ID |
DNC014326
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| Drug Name |
4',4-Dihydroxychalcone
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| Synonyms |
4,4'-Dihydroxychalcone; UNII-CKY3J88Z94; CKY3J88Z94; CHEMBL145927; 1,3-bis(4-hydroxyphenyl)prop-2-en-1-one; 4',4-Dihydroxychalcone; 3600-61-1; 4,4'-Dihydroxybenzylidene acetophenone; RVC 588 (chalcone); 4,4''-dihydroxychalcone; 4'',4-Dihydroxychalcone; AC1NV3S6; (E)-1,3-bis(4-hydroxyphenyl)prop-2-en-1-one; Trans-4,4'-dihydroxychalcone; SCHEMBL773588; (E)-4,4'-Dihydroxychalcone; 4,4'-Dihydroxychalcone, (E)-; 1,3-bis(4-hydroxyphenyl)propenone; ZINC5843955; NSC652891; LMPK12120193; BDBM50068224; AKOS022660924; NSC-652891
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H12O3
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| Canonical SMILES |
C1=CC(=CC=C1C=CC(=O)C2=CC=C(C=C2)O)O
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| InChI |
1S/C15H12O3/c16-13-6-1-11(2-7-13)3-10-15(18)12-4-8-14(17)9-5-12/h1-10,16-17H/b10-3+
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| InChIKey |
FZQLEXXZAVVCCA-XCVCLJGOSA-N
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| CAS Number |
CAS 3600-61-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone. Eur J Med Chem. 2010 May;45(5):2010-7. | |||
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