Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P5SF
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| Drug Name |
Pyrimido-indole derivative 3
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| Synonyms |
PMID26924192-Compound-82
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| Drug Type |
Small molecular drug
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| Company |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H21N5O3
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| Canonical SMILES |
CC1=C(C(=NO1)C)C2=C(C=C3C(=C2)NC4=C3C(=NC(=N4)C)OC5=CC=NC6=CC=CC=C65)OC
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| InChI |
1S/C26H21N5O3/c1-13-23(14(2)34-31-13)18-11-20-17(12-22(18)32-4)24-25(30-20)28-15(3)29-26(24)33-21-9-10-27-19-8-6-5-7-16(19)21/h5-12H,1-4H3,(H,28,29,30)
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| InChIKey |
RYLREOMADHRZEY-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bromodomain and extraterminal domain protein (BET) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Bromodomain and extraterminal domain protein (BET) | Target's Patent Info | [1] | |
| KEGG Pathway | SNARE interactions in vesicular transport | |||
| Reactome | COPII (Coat Protein 2) Mediated Vesicle Transport | |||
| WikiPathways | miR-targeted genes in squamous cell - TarBase | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | BET inhibitors in cancer therapeutics: a patent review.Expert Opin Ther Pat. 2016;26(4):505-22. | |||
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