Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P3SH
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| Former ID |
DIB004851
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| Drug Name |
ReN-1826
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| Synonyms |
Neurotrophin receptor program, Enact; Neurotrophin receptor program, ReNeuron
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| Indication | Central nervous system disease [ICD-11: 8A04-8D87; ICD-10: G00-G99] | Terminated | [1] | |
| Company |
University of Bristol
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neurotrophin-3 (NTF3) | Target Info | Inhibitor | [2] |
| Neurotrophin-4 (NTF4) | Target Info | Inhibitor | [2] | |
| KEGG Pathway | MAPK signaling pathway | |||
| Neurotrophin signaling pathway | ||||
| NetPath Pathway | TNFalpha Signaling Pathway | |||
| Pathway Interaction Database | SHP2 signaling | |||
| p75(NTR)-mediated signaling | ||||
| Neurotrophic factor-mediated Trk receptor signaling | ||||
| Trk receptor signaling mediated by the MAPK pathway | ||||
| WikiPathways | MAPK Signaling Pathway | |||
| Differentiation Pathway | ||||
| BDNF signaling pathway | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017722) | |||
| REF 2 | Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma. J Allergy Clin Immunol. 2006 Sep;118(3):597-605. | |||
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