Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P2BD
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| Former ID |
DIB014008
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| Drug Name |
SAFIRONIL
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| Synonyms |
Hoe-277; Safironil; N,N'-Bis(3-methoxypropyl)pyridine-2,4-dicarboxamide
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| Drug Type |
Small molecular drug
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| Indication | Transplant rejection [ICD-11: NE84; ICD-9: 279.5, 996] | Phase 1 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H23N3O4
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| Canonical SMILES |
COCCCNC(=O)C1=CC(=NC=C1)C(=O)NCCCOC
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| InChI |
1S/C15H23N3O4/c1-21-9-3-6-17-14(19)12-5-8-16-13(11-12)15(20)18-7-4-10-22-2/h5,8,11H,3-4,6-7,9-10H2,1-2H3,(H,17,19)(H,18,20)
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| InChIKey |
HLSXICGBWKECLM-UHFFFAOYSA-N
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| CAS Number |
CAS 134377-69-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prolyl 4-hydroxylasesubunit alpha-1 (P4HA1) | Target Info | Modulator | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antifibrogenic therapies in chronic HCV infection. Curr Drug Targets Infect Disord. 2001 Aug;1(2):227-40. | |||
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