Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P1CE
|
|||
| Former ID |
DCL000099
|
|||
| Drug Name |
CYT 99007
|
|||
| Indication | Acquired immune deficiency syndrome [ICD-11: 1C62.3; ICD-9: 42] | Phase 2 | [1] | |
| Therapeutic Class |
Anticancer Agents
|
|||
| Company |
Cytheris
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin 7 receptor alpha (IL7R) | Target Info | Binder | [2] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| FoxO signaling pathway | ||||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| Primary immunodeficiency | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| IL4 Signaling Pathway | ||||
| TNFalpha Signaling Pathway | ||||
| Leptin Signaling Pathway | ||||
| Reactome | Interleukin-7 signaling | |||
| WikiPathways | Apoptosis-related network due to altered Notch3 in ovarian cancer | |||
| Interleukin-7 signaling | ||||
| TSLP Signaling Pathway | ||||
| IL-7 Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01339000) Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy. U.S. National Institutes of Health. | |||
| REF 2 | Perspectives on interleukin-7 therapy in HIV infection. Curr Opin HIV AIDS. 2007 May;2(3):228-33. | |||
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