Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P0DA
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| Former ID |
DIB000475
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| Drug Name |
BM-162115
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| Synonyms |
115077-66-2; 1,6-Dioxadispiro[4.1.5.1]trideca-8,11-diene-2,10-dione; 1,6-Dioxadispiro(4.1.5.1)trideca-8,11-diene-2,10-dione; BM 162115; ACMC-20ml0u; BM-162115; BM 16.2115; SCHEMBL8797307; AC1L526V; CTK0I0331
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| Drug Type |
Small molecular drug
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Investigative | [1] | |
| Company |
Boehringer Mannheim GmbH
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| Structure |
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Download2D MOL |
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| Formula |
C11H10O4
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| Canonical SMILES |
C1CC2(CC3(O2)C=CC(=O)C=C3)OC1=O
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| InChI |
1S/C11H10O4/c12-8-1-4-10(5-2-8)7-11(15-10)6-3-9(13)14-11/h1-2,4-5H,3,6-7H2
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| InChIKey |
CAZSBBDSSNQJGI-UHFFFAOYSA-N
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| CAS Number |
CAS 115077-66-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phospholipase A2 (PLA2G1B) | Target Info | Inhibitor | [1] |
| BioCyc | Phospholipases | |||
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Ether lipid metabolism | ||||
| Arachidonic acid metabolism | ||||
| Linoleic acid metabolism | ||||
| alpha-Linolenic acid metabolism | ||||
| Metabolic pathways | ||||
| Ras signaling pathway | ||||
| Vascular smooth muscle contraction | ||||
| Pancreatic secretion | ||||
| Fat digestion and absorption | ||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | |||
| Reactome | Acyl chain remodelling of PC | |||
| Acyl chain remodelling of PE | ||||
| Acyl chain remodelling of PI | ||||
| WikiPathways | Glycerophospholipid biosynthesis | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Investigation on the effect of experimental phospholipase A2 inhibitors on the formyl-methionyl-leucyl-phenylalanine-stimulated chemotaxis of human leukocytes in vitro. Arzneimittelforschung. 1998 Jan;48(1):77-81. | |||
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