Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O9UZ
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| Former ID |
DIB013620
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| Drug Name |
Alfimeprase
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| Synonyms |
Thrombolytic fibrolase derivative (cardiovascular diseases), Nuvelo; Thrombolytic fibrolase derivative (cerebrovascular ischemia), Nuvelo; Thrombolytic fibrolase derivative (peripheral arterial occlusive diseases), Nuvelo
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| Indication | Peripheral vascular disease [ICD-11: BD4Z; ICD-10: I73.9; ICD-9: 443.9] | Phase 3 | [1] | |
| Company |
Nuvelo
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fibrin (FG) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00338585) Study of Alfimeprase's Ability to Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery. U.S. National Institutes of Health. | |||
| REF 2 | Disulfide structure of alfimeprase: A recombinant analog of fibrolase. Protein Sci. 2001 June; 10(6): 1264-1267. | |||
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