Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O9BS
|
|||
| Former ID |
DNC013411
|
|||
| Drug Name |
S-2-(o-toluidino)-2-oxoethyl carbamothioate
|
|||
| Synonyms |
5429-04-9; carbamoylsulfanyl-acetic acid o-toluidide; NSC13347; AC1L5DGT; AC1Q5NMD; Oprea1_302154; MLS000085728; CHEMBL236685; ZINC69645; MolPort-002-702-780; HMS2293B23; STK795741; carbamothioic acid, s-[2-[(2-methylphenyl)amino]-2-oxoethyl] ester; NSC-13347; AKOS001735942; MCULE-9952660100; SMR000020857; EU-0051903; SR-01000520769; SR-01000520769-1; S-[2-(2-methylanilino)-2-oxoethyl] carbamothioate; S-{2-[(2-methylphenyl)amino]-2-oxoethyl} thiocarbamate; S-{2-[(2-methylphenyl)amino]-2-oxoethyl} carbamothioate; A1844/0077558
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C10H12N2O2S
|
|||
| Canonical SMILES |
CC1=CC=CC=C1NC(=O)CSC(=O)N
|
|||
| InChI |
1S/C10H12N2O2S/c1-7-4-2-3-5-8(7)12-9(13)6-15-10(11)14/h2-5H,6H2,1H3,(H2,11,14)(H,12,13)
|
|||
| InChIKey |
AGIYBDIJVLUNFI-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 5429-04-9
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of small-molecule inhibitors of tyrosinase. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6871-5. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.