Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O8RG
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| Former ID |
DNC011283
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| Drug Name |
2-phenyl-N-(1-phenylethyl)quinoline-4-carboxamide
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| Synonyms |
CHEMBL274763; 2-phenyl-N-(1-phenylethyl)quinoline-4-carboxamide; AC1ME6SQ; Oprea1_279909; SCHEMBL4477684; MolPort-001-501-804; IEDWYQQEMKCMSQ-UHFFFAOYSA-N; BDBM50074822; STK047893; AKOS022078440; AKOS003267625; MCULE-5320435270; ST45002516; 2-phenyl-N-(1-phenylethyl)-4-quinolinecarboxamide; (2-phenyl(4-quinolyl))-N-(phenylethyl)carboxamide; 2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-ethyl)amide; 2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-ethyl)-amide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C24H20N2O
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| Canonical SMILES |
CC(C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4
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| InChI |
1S/C24H20N2O/c1-17(18-10-4-2-5-11-18)25-24(27)21-16-23(19-12-6-3-7-13-19)26-22-15-9-8-14-20(21)22/h2-17H,1H3,(H,25,27)
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| InChIKey |
IEDWYQQEMKCMSQ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuromedin-K receptor (TACR3) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Reactome | G alpha (q) signalling events | |||
| WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Virtual screening to identify novel antagonists for the G protein-coupled NK3 receptor. J Med Chem. 2010 Nov 25;53(22):8080-8. | |||
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