Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O6KE
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| Former ID |
DIB004205
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| Drug Name |
Repirinast
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| Synonyms |
MY-1250; MY-5116; MY-6116
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| Drug Type |
Small molecular drug
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Approved | [1] | |
| Company |
Mitsubishi-Tokyo Pharmaceuticals Inc
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| Structure |
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Download2D MOL |
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| Formula |
C20H21NO5
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| Canonical SMILES |
CC1=C(C2=C(C=C1)C3=C(C(=O)C=C(O3)C(=O)OCCC(C)C)C(=O)N2)C
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| InChI |
1S/C20H21NO5/c1-10(2)7-8-25-20(24)15-9-14(22)16-18(26-15)13-6-5-11(3)12(4)17(13)21-19(16)23/h5-6,9-10H,7-8H2,1-4H3,(H,21,23)
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| InChIKey |
NFQIAEMCQGTTIR-UHFFFAOYSA-N
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| CAS Number |
CAS 73080-51-0
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:32092
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine receptor (HR) | Target Info | Modulator | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Mechanism of action of MY-1250, an active metabolite of Repirinast, in inhibiting histamine release from rat mast cells. Br J Pharmacol. 1992 Mar;105(3):587-90. | |||
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