Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O3TC
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| Former ID |
DIB006481
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| Drug Name |
FK-962
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| Synonyms |
FK-960 analog, Fujisawa
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| Drug Type |
Small molecular drug
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| Indication | Alzheimer disease [ICD-11: 8A20; ICD-10: G30, G30.9; ICD-9: 331] | Phase 2 | [1] | |
| Company |
Fujisawa Pharmaceutical Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C15H18FNO2
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| Canonical SMILES |
CC(=O)C1CCC(CC1)NC(=O)C2=CC=C(C=C2)F
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| InChI |
1S/C15H18FNO2/c1-10(18)11-4-8-14(9-5-11)17-15(19)12-2-6-13(16)7-3-12/h2-3,6-7,11,14H,4-5,8-9H2,1H3,(H,17,19)
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| InChIKey |
PYMCWQVGVQEZNO-UHFFFAOYSA-N
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| CAS Number |
CAS 283167-06-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Somatostatin receptor (SSTR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00087724) A Randomized Study to Evaluate FK962 in Subjects With Mild to Moderate Alzheimer's Disease. U.S. National Institutes of Health. | |||
| REF 2 | FK960, a novel potential anti-dementia drug, enhances high K(+)-evoked release of somatostatin from rat hippocampal slices. Brain Res. 2001 Feb 16;892(1):111-7. | |||
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