Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0O0JO
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| Former ID |
DNC011256
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| Drug Name |
N-(2-chlorobenzyl)-5-(4-chlorophenyl)nicotinamide
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| Synonyms |
CHEMBL1269883; N-(2-chlorobenzyl)-5-(4-chlorophenyl)nicotinamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C19H14Cl2N2O
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| Canonical SMILES |
C1=CC=C(C(=C1)CNC(=O)C2=CN=CC(=C2)C3=CC=C(C=C3)Cl)Cl
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| InChI |
1S/C19H14Cl2N2O/c20-17-7-5-13(6-8-17)15-9-16(11-22-10-15)19(24)23-12-14-3-1-2-4-18(14)21/h1-11H,12H2,(H,23,24)
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| InChIKey |
CKNIOMWTEPBNFF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.8 (SCN10A) | Target Info | Inhibitor | [1] |
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6812-5. | |||
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