Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0NR7H
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| Former ID |
DPR000007
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| Drug Name |
A-837093
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| Synonyms |
3,4-dihydro-naphthalen-1-olate
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| Drug Type |
Small molecular drug
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| Indication | Hepatitis C virus infection [ICD-11: 1E51.1; ICD-10: B18.2] | Phase 1 | [1] | |
| Company |
Abbott
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| Structure |
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Download2D MOL |
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| Formula |
C24H27N3O6S2
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| Canonical SMILES |
CC(C)CCC1(C2=CC=CC=C2C(=C(C1=O)C3=NS(=O)(=O)C4=C(N3)C=CC(=C4)NS(=O)(=O)C)O)C
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| InChI |
1S/C24H27N3O6S2/c1-14(2)11-12-24(3)17-8-6-5-7-16(17)21(28)20(22(24)29)23-25-18-10-9-15(26-34(4,30)31)13-19(18)35(32,33)27-23/h5-10,13-14,26,28H,11-12H2,1-4H3,(H,25,27)/t24-/m1/s1
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| InChIKey |
ZTRJLSWOQIDJIS-XMMPIXPASA-N
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| CAS Number |
CAS 847442-84-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepatitis C virus RNA-directed RNA polymerase (HCV NS5B) | Target Info | Inhibitor | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for hepatitis C. Expert Opin Emerg Drugs. 2008 Mar;13(1):1-19. | |||
| REF 2 | Activity of a potent hepatitis C virus polymerase inhibitor in the chimpanzee model. Antimicrob Agents Chemother. 2007 Dec;51(12):4290-6. | |||
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