Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0NR3V
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| Former ID |
DIB011769
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| Drug Name |
Zatebradine
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| Synonyms |
UL-FS-49; UL-FS-49CL
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|
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| Drug Type |
Small molecular drug
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| Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Terminated | [1], [2] | |
| Company |
Boehringer Ingelheim Corp
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H36N2O5
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| Canonical SMILES |
CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)CCC3=CC(=C(C=C3)OC)OC
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| InChI |
1S/C26H36N2O5/c1-27(13-9-19-7-8-22(30-2)23(15-19)31-3)11-6-12-28-14-10-20-16-24(32-4)25(33-5)17-21(20)18-26(28)29/h7-8,15-17H,6,9-14,18H2,1-5H3
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| InChIKey |
KEDQCFRVSHYKLR-UHFFFAOYSA-N
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| CAS Number |
CAS 85175-67-3
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:93613
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv1.5 (KCNA5) | Target Info | Modulator | [3] |
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Voltage gated Potassium channels | |||
| WikiPathways | Potassium Channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2358). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000429) | |||
| REF 3 | DOI: 10.1161/01.CIR.94.3.562 | |||
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