Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0NF7S
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| Former ID |
DIB012032
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| Drug Name |
R-59494
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| Synonyms |
R 59494; 136917-41-4; AC1L307W; DTXSID50160007; N-Methyl-N-(1-(4-phenoxybutyl)-3-pyrrolidinyl)-2-benzothiazolamine; N-methyl-N-[1-(4-phenoxybutyl)pyrrol-3-yl]-1,3-benzothiazol-2-amine; 2-Benzothiazolamine, N-methyl-N-(1-(4-phenoxybutyl)-1H-pyrrol-3-yl)-
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| Drug Type |
Small molecular drug
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| Indication | Ischemia [ICD-11: 8B10-8B11; ICD-9: 459.89] | Terminated | [1] | |
| Company |
Janssen Pharmaceutica NV
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H23N3OS
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| Canonical SMILES |
CN(C1=CN(C=C1)CCCCOC2=CC=CC=C2)C3=NC4=CC=CC=C4S3
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| InChI |
1S/C22H23N3OS/c1-24(22-23-20-11-5-6-12-21(20)27-22)18-13-15-25(17-18)14-7-8-16-26-19-9-3-2-4-10-19/h2-6,9-13,15,17H,7-8,14,16H2,1H3
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| InChIKey |
PFBZXLGUUGDBNI-UHFFFAOYSA-N
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| CAS Number |
CAS 136917-41-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Modulator | [2] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002300) | |||
| REF 2 | Veratridine activates a silent sodium channel in rat isolated aorta. Eur J Pharmacol. 1992 Aug 25;219(2):253-9. | |||
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