Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0ND2Y
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| Former ID |
DNC011941
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| Drug Name |
1-(3-Nitro-phenyl)-piperazine
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| Synonyms |
1-(3-nitrophenyl)piperazine; 54054-85-2; 1-(3-Nitro-phenyl)-piperazine; 1-(3-nitrophenyl)-piperazine; CHEMBL267153; Piperazine, 1-(3-nitrophenyl)-; (3-nitrophenyl)piperazine; 3-nitrophenylpiperazine; AC1Q1X8X; AC1MC26R; SCHEMBL519878; Piperazine,1-(3-nitrophenyl)-; CTK4J9414; DTXSID20375060; MolPort-000-005-114; LHHZRIYUOZPKSG-UHFFFAOYSA-N; ZINC4244898; SBB055462; CN-052; BDBM50017449; ANW-49084; AKOS003587736; CS-W019388; MCULE-2930089958; BR-49879; AN-40610; KB-63925; AJ-49640; RT-006025; DB-024583; AB0025386; W6842; FT-0660276
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H13N3O2
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| Canonical SMILES |
C1CN(CCN1)C2=CC(=CC=C2)[N+](=O)[O-]
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| InChI |
1S/C10H13N3O2/c14-13(15)10-3-1-2-9(8-10)12-6-4-11-5-7-12/h1-3,8,11H,4-7H2
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| InChIKey |
LHHZRIYUOZPKSG-UHFFFAOYSA-N
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| CAS Number |
CAS 54054-85-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
| 5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| SIDS Susceptibility Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. J Med Chem. 1989 May;32(5):1052-6. | |||
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