Drug Information
Drug General Information | Top | |||
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Drug ID |
D0N4SF
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Former ID |
DNCL002132
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Drug Name |
GI-4000
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Drug Type |
Vaccine
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Indication | Colorectal cancer [ICD-11: 2B91.Z] | Phase 2 | [1] | |
Pancreatic cancer [ICD-11: 2C10] | Phase 2 | [2] | ||
Company |
GlobeImmune
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References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT00655161) A Pilot Phase 2 Trial of the Immunogenicity, and Safety of GI-4000; an Inactivated Recombinant S. Cerevisiae Expressing Mutant Ras Protein, as Consolidation Therapy Following Curative Treatment for Stage I-III Non-Small Cell Lung Cancer (NSCLC) With Tumor Sequence Confirmation of K-ras Mutation. U.S. National Institutes of Health. | |||
REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
REF 3 | Phase II study of the GI-4000 KRAS vaccine after curative therapy in patients with stage I-III lung adenocarcinoma harboring a KRAS G12C, G12D, or G12V mutation. Clin Lung Cancer. 2014 Nov;15(6):405-10. |
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