Drug Information
Drug General Information | Top | |||
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Drug ID |
D0N3YN
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Former ID |
DIB020607
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Drug Name |
ONO-3080573
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Synonyms |
ON3
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C31H34O7
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Canonical SMILES |
CC1=C(C=C(C=C1OC)C(C(COC2=CC=C(C=C2)C3(CC3)C(=O)O)OC4CC5=CC=CC=C5C4)O)OC
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InChI |
1S/C31H34O7/c1-19-26(35-2)16-22(17-27(19)36-3)29(32)28(38-25-14-20-6-4-5-7-21(20)15-25)18-37-24-10-8-23(9-11-24)31(12-13-31)30(33)34/h4-11,16-17,25,28-29,32H,12-15,18H2,1-3H3,(H,33,34)/t28-,29+/m0/s1
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InChIKey |
FVESDCZDESZGHA-URLMMPGGSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Lysophosphatidic acid receptor 1 (LPAR1) | Target Info | Antagonist | [1] |
KEGG Pathway | Rap1 signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
PI3K-Akt signaling pathway | ||||
Gap junction | ||||
Pathways in cancer | ||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
Pathway Interaction Database | LPA receptor mediated events | |||
Reactome | G alpha (q) signalling events | |||
G alpha (i) signalling events | ||||
Lysosphingolipid and LPA receptors | ||||
WikiPathways | Myometrial Relaxation and Contraction Pathways | |||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
Small Ligand GPCRs | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 2015 Jun 18;161(7):1633-43. |
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