Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0MT7W
|
|||
| Former ID |
DNCL003677
|
|||
| Drug Name |
NN8210
|
|||
| Indication | Rheumatoid arthritis [ICD-11: FA20] | Discontinued in Phase 1 | [1] | |
| Company |
Novo Nordisk
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | C5a anaphylatoxin chemotactic receptor (C5AR1) | Target Info | Modulator | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Complement and coagulation cascades | ||||
| Staphylococcus aureus infection | ||||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Complement and Coagulation Cascades | |||
| Human Complement System | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800036376) | |||
| REF 2 | Complement in immune and inflammatory disorders: therapeutic interventions. J Immunol. 2013 Apr 15;190(8):3839-47. | |||
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