Drug Information
Drug General Information | Top | |||
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Drug ID |
D0MA2E
|
|||
Drug Name |
GLYCAR T cells
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|||
Drug Type |
CAR T Cell Therapy
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Indication | Hepatocellular carcinoma [ICD-11: 2C12.02; ICD-10: C22.0; ICD-9: 155] | Phase 1 | [1] | |
Company |
Baylor College of Medicine
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Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Glypican-3 (GPC3) | Target Info | CAR-T-Cell-Therapy | [1] |
KEGG Pathway | Proteoglycans in cancer | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Glypican pathway | |||
Glypican 3 network | ||||
Reactome | A tetrasaccharide linker sequence is required for GAG synthesis | |||
HS-GAG degradation | ||||
Retinoid metabolism and transport | ||||
WikiPathways | Visual phototransduction |
References | Top | |||
---|---|---|---|---|
REF 1 | ClinicalTrials.gov (NCT02905188) Glypican 3-specific Chimeric Antigen Receptor Expressing T Cells for Hepatocellular Carcinoma (GLYCAR) |
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