Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0M9RF
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| Former ID |
DIB018587
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| Drug Name |
3570-0208
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| Synonyms |
[6-ethyl-2-methyl-3-(1-methylbenzimidazol-2-yl)-4-oxochromen-7-yl] acetate; UNM000003536701; AC1MJIQD; BAS 00135206; Oprea1_681432; Oprea1_151337; MLS001242385; GTPL5828; CHEMBL1329101; cid_3092570; CHEBI:92290; BDBM40404; ML048; HMS2231A24; HMS3372G14; ZINC4247033; STK922580; AKOS000525202; MCULE-3542011334; SMR000686159; ST50330694; EU-0040874; SR-01000456743; SR-01000456743-1; 3570-0208 [PMID:19807662]; 2-methyl-3-(1-methyl-2-benzimidazolyl)-6-ethyl-7-acetoxychromone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL
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| Formula |
C22H20N2O4
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| Canonical SMILES |
CCC1=CC2=C(C=C1OC(=O)C)OC(=C(C2=O)C3=NC4=CC=CC=C4N3C)C
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| InChI |
1S/C22H20N2O4/c1-5-14-10-15-19(11-18(14)28-13(3)25)27-12(2)20(21(15)26)22-23-16-8-6-7-9-17(16)24(22)4/h6-11H,5H2,1-4H3
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| InChIKey |
HTTVYKXJCQENKW-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:92290
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-formyl peptide receptor (FPR1) | Target Info | Antagonist | [1] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Staphylococcus aureus infection | ||||
| NetPath Pathway | Leptin Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||
| Reactome | G alpha (i) signalling events | |||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Human Complement System | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of selective probes and antagonists for G-protein-coupled receptors FPR/FPRL1 and GPR30. Curr Top Med Chem. 2009;9(13):1227-36. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5828). | |||
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