Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0M9DT
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| Former ID |
DNC009730
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| Drug Name |
DIMETHYLSPINGOSINE
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| Synonyms |
N,N-Dimethylsphing-4-enine; D-erythro-N,N-dimethylsphingosine; N,N-Dimethylspingosine; CHEMBL322333; CHEBI:78759; D-erythro-Sphingosine, N,N-Dimethyl-; N,N-Dimethylsphingenine; N,N-dimethyl-erythro-sphingosine; N,N-Dimethyl-D-erythrosphingenine; N-dimethylsphingosine; AC1NQZUP; C13914; N,N-Dimethyl-4-sphingenine; BSPBio_001420; N,N-Dimethylsphingosine, oil; SCHEMBL121927; SCHEMBL5493697; BML3-C12; Dimethyl Sphingosine (d18:1)
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H41NO2
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| Canonical SMILES |
CCCCCCCCCCCCCC=CC(C(CO)N(C)C)O
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| InChI |
1S/C20H41NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)19(18-22)21(2)3/h16-17,19-20,22-23H,4-15,18H2,1-3H3/b17-16+/t19-,20+/m0/s1
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| InChIKey |
YRXOQXUDKDCXME-YIVRLKKSSA-N
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| CAS Number |
CAS 119567-63-4
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:78759
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine kinase 2 (SPHK2) | Target Info | Inhibitor | [1] |
| BioCyc | Sphingosine and sphingosine-1-phosphate metabolism | |||
| KEGG Pathway | Sphingolipid metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| VEGF signaling pathway | ||||
| Fc gamma R-mediated phagocytosis | ||||
| Tuberculosis | ||||
| Panther Pathway | Angiogenesis | |||
| VEGF signaling pathway | ||||
| Pathwhiz Pathway | Sphingolipid Metabolism | |||
| Pathway Interaction Database | IL12-mediated signaling events | |||
| Ceramide signaling pathway | ||||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| Reactome | Sphingolipid de novo biosynthesis | |||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Sphingolipid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases. J Med Chem. 2009 Jun 25;52(12):3618-26. | |||
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