Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M8HH
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| Former ID |
DIB002951
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| Drug Name |
PUMAPRAZOLE
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| Synonyms |
BY-841; Pumaprazole; N-[2-(2,3-Dimethylimidazol[1,2-a]pyridin-8-ylaminomethyl)-3-methylphenyl]carbamic acid methyl ester
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| Drug Type |
Small molecular drug
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| Indication | Duodenal ulcer [ICD-11: DA63] | Discontinued in Phase 3 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C19H22N4O2
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| Canonical SMILES |
CC1=C(C(=CC=C1)NC(=O)OC)CNC2=CC=CN3C2=NC(=C3C)C
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| InChI |
1S/C19H22N4O2/c1-12-7-5-8-16(22-19(24)25-4)15(12)11-20-17-9-6-10-23-14(3)13(2)21-18(17)23/h5-10,20H,11H2,1-4H3,(H,22,24)
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| InChIKey |
NZQTVUWEPPDOKK-UHFFFAOYSA-N
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| CAS Number |
CAS 158364-59-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gastric H(+)/K(+) ATPase (Proton pump) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005537) | |||
| REF 2 | Effects of pumaprazole (BY841), a novel reversible proton pump antagonist, and of omeprazole, on intragastric acidity before and after cure of Heli... Aliment Pharmacol Ther. 1999 Jan;13(1):27-34. | |||
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