Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M7DS
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| Former ID |
DIB003431
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| Drug Name |
Valomaciclovir stearate
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| Synonyms |
Omaciclovir; Valomaciclovir; A 174606.0; A 182091.0; ABT-091; ABT-606; Anti-VZV drug; EPB-348; MIV-606; RP-606; A-174606.6; ABT-182091.0; 2HM-HBG
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| Drug Type |
Small molecular drug
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| Indication | Varicella zoster virus infection [ICD-11: 1E91] | Phase 2 | [1] | |
| Company |
Medivir AB
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| Structure |
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Download2D MOL
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| Formula |
C33H58N6O5
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| Canonical SMILES |
CCCCCCCCCCCCCCCCCC(=O)OCC(CCOC(=O)C(C(C)C)N)CN1C=NC2=C1N=C(NC2=O)N
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| InChI |
1S/C33H58N6O5/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-27(40)44-23-26(20-21-43-32(42)28(34)25(2)3)22-39-24-36-29-30(39)37-33(35)38-31(29)41/h24-26,28H,4-23,34H2,1-3H3,(H3,35,37,38,41)/t26-,28+/m1/s1
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| InChIKey |
ACBSZTQIFTYFGH-IAPPQJPRSA-N
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| CAS Number |
CAS 195156-77-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Herpes simplex virus DNA polymerase UL30 (HSV UL30) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00831103) A Phase 2b Trial of EPB-348 for the Treatment of Herpes Zoster. U.S. National Institutes of Health. | |||
| REF 2 | Progress in the Development of New Therapies for Herpesvirus Infections. Curr Opin Virol. 2011 December 1; 1(6): 548-554. | |||
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