Drug Information
Drug General Information | Top | |||
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Drug ID |
D0M7BT
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Former ID |
DAP001295
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Drug Name |
Doxapram
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Synonyms |
Docatone; Dopram; Doxapramum; Doxapram HCL; Doxapram hydrochloride; Docatone (TN); Dopram (TN); Doxapram (INN); Doxapram [USP:JAN]; Doxapramum [INN-Latin]; (+-)-doxapram; 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone; 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one; 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one; 2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl-(9CI)
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Drug Type |
Small molecular drug
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Indication | Respiratory disease [ICD-11: CB40] | Approved | [1], [2], [3] | |
Therapeutic Class |
Central Nervous System Stimulants
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Structure |
Download2D MOL |
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Formula |
C24H30N2O2
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Canonical SMILES |
CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4
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InChI |
1S/C24H30N2O2/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,22H,2,13-19H2,1H3
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InChIKey |
XFDJYSQDBULQSI-UHFFFAOYSA-N
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CAS Number |
CAS 309-29-5
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PubChem Compound ID | ||||
PubChem Substance ID |
4407397, 8152010, 10518045, 15078242, 29222298, 46506829, 47255198, 48415922, 50039760, 50112713, 57288771, 57321639, 77984260, 92711739, 93608329, 94569105, 96024569, 103707721, 104302687, 117878565, 125823429, 126630565, 126688224, 131549338, 134223083, 134338518, 134408901, 134974467, 136946452, 137102167, 140881997, 144115921, 152227757, 160814282, 160963906, 162192829, 163193312, 163372621, 166234095, 172868226, 177749127, 178103744, 179225358, 179499729, 184685748, 198994099, 204422700, 210279719, 210282042, 223667437
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ChEBI ID |
CHEBI:681848
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ADReCS Drug ID | BADD_D00716 ; BADD_D00717 | |||
SuperDrug ATC ID |
R07AB01
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SuperDrug CAS ID |
cas=000309295
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Target and Pathway | Top | |||
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Target(s) | Peripheral carotid chemoreceptor (PCC) | Target Info | Stimulator | [4] |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7169). | |||
REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 073529. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
REF 4 | Ovalbumin sensitization alters the ventilatory responses to chemical challenges in guinea pigs. J Appl Physiol (1985). 2005 Nov;99(5):1782-8. |
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