Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M4FW
|
|||
| Former ID |
DNC001440
|
|||
| Drug Name |
THPO
|
|||
| Synonyms |
THPO; 53602-00-9; 4,5,6,7-Tetrahydroisoxazolo(4,5-c)pyridin-3-ol; 4,5,6,7-Tetrahydroisoxazolo[4,5-c]pyridin-3-ol; CHEMBL150830; Isoxazolo(4,5-d)pyridin-3(2H)-one, 4,5,6,7-tetrahydro-; 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3(2H)-one; AC1Q6C1M; SCHEMBL455554; GTPL4727; AC1L1C13; isoxazolo[4,5-c]pyridin-3-ol, 4,5,6,7-tetrahydro-; CTK4J8459; DTXSID90201822; SXXLKZCNJHJYFL-UHFFFAOYSA-N; FCH907083; BDBM50226145; ZINC13803345; AKOS022718554; AKOS006371191; API0009745; DA-05117; LS-183574; FT-0754243
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C6H8N2O2
|
|||
| Canonical SMILES |
C1CNCC2=C1ONC2=O
|
|||
| InChI |
1S/C6H8N2O2/c9-6-4-3-7-2-1-5(4)10-8-6/h7H,1-3H2,(H,8,9)
|
|||
| InChIKey |
SXXLKZCNJHJYFL-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 53602-00-9
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| SuperDrug ATC ID |
J05AF03
|
|||
| SuperDrug CAS ID |
cas=007481892
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid uptake (GABAU) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4727). | |||
| REF 2 | Anticonvulsant activity of intracerebroventricularly administered glial GABA uptake inhibitors and other GABAmimetics in chemical seizure models. Epilepsy Res. 1989 Jul-Aug;4(1):34-41. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.