Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M3MN
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| Former ID |
DAP001244
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| Drug Name |
Leucovorin/5-fluorouracil
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| Drug Type |
Small molecular drug
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| Indication | Colon cancer [ICD-11: 2B90.Z] | Approved | [1] | |
| Therapeutic Class |
Vitamins
|
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| Structure |
 |
Download2D MOL |
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| Canonical SMILES |
C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| SuperDrug ATC ID |
V03AF03
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| SuperDrug CAS ID |
cas=001492188
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 2 | Decreased levels of UMP kinase as a mechanism of fluoropyrimidine resistance. Mol Cancer Ther. 2009 May;8(5):1037-44. | |||
| REF 3 | Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil. Is it time to move forward Cancer Biol Ther. 2008 Jul;7(7):986-94. | |||
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