Drug Information
Drug General Information | Top | |||
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Drug ID |
D0M3LK
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Former ID |
DIB018990
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Drug Name |
BMS270394
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Synonyms |
BMS 961; BMS-270394; BMS 270394
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C23H26FNO4
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Canonical SMILES |
CC1(CCC(C2=C1C=CC(=C2)C(C(=O)NC3=C(C=C(C=C3)C(=O)O)F)O)(C)C)C
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InChI |
1S/C23H26FNO4/c1-22(2)9-10-23(3,4)16-11-13(5-7-15(16)22)19(26)20(27)25-18-8-6-14(21(28)29)12-17(18)24/h5-8,11-12,19,26H,9-10H2,1-4H3,(H,25,27)(H,28,29)/t19-/m1/s1
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InChIKey |
AANFHDFOMFRLLR-LJQANCHMSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Retinoic acid receptor gamma (RARG) | Target Info | Agonist | [2] |
Reactome | Nuclear Receptor transcription pathway | |||
WikiPathways | Vitamin A and Carotenoid Metabolism | |||
Nuclear Receptors in Lipid Metabolism and Toxicity | ||||
Mesodermal Commitment Pathway | ||||
Endoderm Differentiation | ||||
Nuclear Receptors |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2653). | |||
REF 2 | Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6322-7. |
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