Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0LT2N
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| Drug Name |
ZNFTXQFGUIKQQE-UHFFFAOYSA-N
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| Synonyms |
CHEMBL1076708; 6-[cyclohexyl(ethyl)amino]-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide; 6-(cyclohexyl(ethyl)amino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide; SCHEMBL3029985; ZNFTXQFGUIKQQE-UHFFFAOYSA-N; BDBM50313322
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C20H26N4O2
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| Canonical SMILES |
CCN(C1CCCCC1)C2=NC=NC(=C2)C(=O)NC3=C(C=C(C=C3)O)C
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| InChI |
1S/C20H26N4O2/c1-3-24(15-7-5-4-6-8-15)19-12-18(21-13-22-19)20(26)23-17-10-9-16(25)11-14(17)2/h9-13,15,25H,3-8H2,1-2H3,(H,23,26)
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| InChIKey |
ZNFTXQFGUIKQQE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target's Patent Info | [1] | |
| KEGG Pathway | Sphingolipid signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | S1P3 pathway | |||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| Reactome | G alpha (i) signalling events | |||
| Lysosphingolipid and LPA receptors | ||||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
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| REF 1 | 6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis. US9150519. | |||
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