Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0LR4B
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| Former ID |
DIB006702
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| Drug Name |
Loxoprofen gel
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| Synonyms |
Loxonin; Loxoprofen; Loxonin Pap; Loxonin Tape; CS-600G; LX-A; LX-P; Loxonin Gel 1%; Lipoxin A, Daiichi Sankyo/Lead Chemical; Lipoxin A, Sankyo/ Lead Chemical; Loxoprofen (gel, pain/ inflammation), Daiichi Sankyo; Loxoprofen (gel, pain/ inflammation), Sankyo; Loxoprofen (patch, pain/inflammation), Daiichi Sankyo/ Lead Chemical; Loxoprofen (patch, pain/inflammation), Sankyo/ Lead Chemical
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| Drug Type |
Small molecular drug
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Approved | [1], [2] | |
| Company |
Sankyo Co Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C15H18O3
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| Canonical SMILES |
CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)O
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| InChI |
1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
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| InChIKey |
YMBXTVYHTMGZDW-UHFFFAOYSA-N
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| CAS Number |
68767-14-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase (COX) | Target Info | Inhibitor | [1], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | ClinicalTrials.gov (NCT00994461) Study Of Celecoxib In Healthy Subjects. U.S. National Institutes of Health. | |||
| REF 3 | Comparative study of the clinical efficacy of the selective cyclooxygenase-2 inhibitor celecoxib compared with loxoprofen in patients with frozen shoulder. Mod Rheumatol. 2014 Jan;24(1):144-9. | |||
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