Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0LN2D
|
|||
| Former ID |
DNC012964
|
|||
| Drug Name |
ETHIONINE
|
|||
| Synonyms |
L-Ethionine; Ethionine; 13073-35-3; S-Ethyl-L-homocysteine; (S)-2-amino-4-(ethylthio)butanoic acid; L-S-Ethylhomocysteine; Homocysteine, S-ethyl-; L-Homocysteine, S-ethyl-; Ethionine (VAN); L-2-Amino-4-(ethylthio)butyric acid; UNII-WX1BN24WZT; (L)-Ethionine; (+)-ethionine; NSC 82393; CCRIS 289; C6H13NO2S; HSDB 5080; Butyric acid, 2-amino-4-(ethylthio)-, L-; EINECS 235-966-4; WX1BN24WZT; Butanoic acid, 2-amino-4-(ethylthio)-, (S)-; BRN 1722528; (+)-S-ethyl-L-homocysteine; CHEMBL203187; CHEBI:4886; Butyric acid, 2-amino-4-(ethylene)-
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C6H13NO2S
|
|||
| Canonical SMILES |
CCSCCC(C(=O)O)N
|
|||
| InChI |
1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
|
|||
| InChIKey |
GGLZPLKKBSSKCX-YFKPBYRVSA-N
|
|||
| CAS Number |
CAS 13073-35-3
|
|||
| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:4886
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cardiac muscle contraction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Oxytocin signaling pathway | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||
| WikiPathways | Arrhythmogenic Right Ventricular Cardiomyopathy | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.