Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0LJ9D
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| Former ID |
DNC011110
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| Drug Name |
4-(4-(thiophen-2-yl)benzyl)pyridine
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| Synonyms |
CHEMBL1214736; 4-(4-(thiophen-2-yl)benzyl)pyridine; SCHEMBL18770350
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H13NS
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| Canonical SMILES |
C1=CSC(=C1)C2=CC=C(C=C2)CC3=CC=NC=C3
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| InChI |
1S/C16H13NS/c1-2-16(18-11-1)15-5-3-13(4-6-15)12-14-7-9-17-10-8-14/h1-11H,12H2
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| InChIKey |
ORQOALYZYXEWJV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] | |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| Androgen biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| Prolactin signaling pathway | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Androgen and Estrogen Metabolism | ||||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| Androgen biosynthesis | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| Steroid Biosynthesis | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| Prostate Cancer | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Replacement of imidazolyl by pyridyl in biphenylmethylenes results in selective CYP17 and dual CYP17/CYP11B1 inhibitors for the treatment of prosta... J Med Chem. 2010 Aug 12;53(15):5749-58. | |||
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