Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0LH1A
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| Former ID |
DNC000441
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| Drug Name |
CL 385319
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| Synonyms |
CHEMBL2088468; cl-385319
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2], [3], [4] | |
| Structure |
 |
Download2D MOL
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| Formula |
C15H19ClF4N2O
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| Canonical SMILES |
C1CCN(CC1)CCNC(=O)C2=CC(=CC(=C2)F)C(F)(F)F.Cl
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| InChI |
1S/C15H18F4N2O.ClH/c16-13-9-11(8-12(10-13)15(17,18)19)14(22)20-4-7-21-5-2-1-3-6-21;/h8-10H,1-7H2,(H,20,22);1H
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| InChIKey |
FEMIHMMAZDXYBI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Influenza Hemagglutinin (Influ HA) | Target Info | Inhibitor | [1], [2], [3], [4] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17736-41. | |||
| REF 2 | Novel stachyflin derivatives from Stachybotrys sp. RF-7260. Fermentation, isolation, structure elucidation and biological activities. J Antibiot (Tokyo). 2002 Mar;55(3):239-48. | |||
| REF 3 | An approach to the identification of potent inhibitors of influenza virus fusion using parallel synthesis methodology. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2393-6. | |||
| REF 4 | Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin. J Virol. 1999 Jan;73(1):140-51. | |||
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