Drug Information
Drug General Information | Top | |||
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Drug ID |
D0LE1F
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Former ID |
DIB018316
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Drug Name |
[3H]L655708
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Synonyms |
YKYOQIXTECBVBB-UHFFFAOYSA-N; ethyl 15-methoxy-12-oxo-2,4,11-triazatetracyclo[11400^{2,6}0^{7,11}]heptadeca-1(13),3,5,14,16-pentaene-5-carboxylate; AC1N5TG4; GTPL4363; GTPL4238; CHEBI:91920; HMS3267P07
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H19N3O4
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Canonical SMILES |
CCOC(=O)C1=C2C3CCCN3C(=O)C4=C(N2C=N1)C=CC(=C4)OC
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InChI |
1S/C18H19N3O4/c1-3-25-18(23)15-16-14-5-4-8-20(14)17(22)12-9-11(24-2)6-7-13(12)21(16)10-19-15/h6-7,9-10,14H,3-5,8H2,1-2H3
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InChIKey |
YKYOQIXTECBVBB-UHFFFAOYSA-N
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:91920
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Target and Pathway | Top | |||
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Target(s) | GABA(A) receptor alpha-5 (GABRA5) | Target Info | Modulator (allosteric modulator) | [2] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Retrograde endocannabinoid signaling | ||||
GABAergic synapse | ||||
Morphine addiction | ||||
Nicotine addiction | ||||
Reactome | Ligand-gated ion channel transport | |||
GABA A receptor activation | ||||
WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
Iron uptake and transport |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4363). | |||
REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 408). |
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