Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0L8KL
|
|||
| Former ID |
DNC005745
|
|||
| Drug Name |
5-Naphthalen-2-yl-oxazole
|
|||
| Synonyms |
143659-20-5; 5-(naphthalen-2-yl)-1,3-oxazole; 5-(2-naphthalenyl)Oxazole; 5-(Naphthalen-2-yl)oxazole; Oxazole,5-(2-naphthalenyl)-; 5-(2-naphthyl)-1,3-oxazole; 5-(2-Naphthyl)oxazole; ACMC-1C0FI; 5-(2-naph-thyl-)oxazol; SCHEMBL4500585; BDBM8928; CHEMBL193653; 5-Naphth-2-yl-1,3-oxazole; CTK4C3747; DTXSID10460853; MolPort-001-758-948; UQGCSVOKHFBQIP-UHFFFAOYSA-N; oxazole-substituted naphthalene 29; KS-00001PB5; ZX-AT019030; ZINC13674492; AKOS005254941; MCULE-4854701546; OR12565; GL-1006; KB-269976; AX8104945; DB-057999
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C13H9NO
|
|||
| Canonical SMILES |
C1=CC=C2C=C(C=CC2=C1)C3=CN=CO3
|
|||
| InChI |
1S/C13H9NO/c1-2-4-11-7-12(6-5-10(11)3-1)13-8-14-9-15-13/h1-9H
|
|||
| InChIKey |
UQGCSVOKHFBQIP-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 143659-20-5
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart fa... J Med Chem. 2005 Oct 20;48(21):6632-42. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.