Drug Information
Drug General Information | Top | |||
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Drug ID |
D0L4WN
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Former ID |
DNC010365
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Drug Name |
1,4-diaminoanthracene-9,10-dione
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Synonyms |
1,4-Diaminoanthraquinone; 128-95-0; 1,4-diaminoanthracene-9,10-dione; Disperse violet 1; Krisolamine; 1,4-Diamino anthraquinone; Grasol Violet R; Seacyl Violet R; Acetate Red Violet R; 9,10-Anthracenedione, 1,4-diamino-; Setacyl Violet R; Oil Violet R; Disperse Violet K; Resiren Violet TR; Oracet Violet 2R; Gracet Violet 2R; Setile Violet 3R; Duranol Violet 2R; Nacelan Violet 4R; Cibacet Violet 2R; Amacel heliotrope R; Dispersive Violet K; Solvent Violet 11; Cibacete Violet 2R; Perliton Violet 3R; Nyloquinone Violet R; Artisil Viole
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H10N2O2
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Canonical SMILES |
C1=CC=C2C(=C1)C(=O)C3=C(C=CC(=C3C2=O)N)N
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InChI |
1S/C14H10N2O2/c15-9-5-6-10(16)12-11(9)13(17)7-3-1-2-4-8(7)14(12)18/h1-6H,15-16H2
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InChIKey |
FBMQNRKSAWNXBT-UHFFFAOYSA-N
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CAS Number |
CAS 128-95-0
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Adenosine A2a receptor (ADORA2A) | Target Info | Inhibitor | [1] |
KEGG Pathway | Rap1 signaling pathway | |||
Calcium signaling pathway | ||||
cAMP signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Vascular smooth muscle contraction | ||||
Parkinson's disease | ||||
Alcoholism | ||||
Pathwhiz Pathway | Intracellular Signalling Through Adenosine Receptor A2a and Adenosine | |||
Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
Reactome | NGF-independant TRKA activation | |||
Adenosine P1 receptors | ||||
G alpha (s) signalling events | ||||
Surfactant metabolism | ||||
WikiPathways | Nucleotide GPCRs | |||
Monoamine Transport | ||||
GPCRs, Class A Rhodopsin-like | ||||
NGF signalling via TRKA from the plasma membrane | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. J Med Chem. 2010 Feb 25;53(4):1799-809. |
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