Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0L2JM
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| Former ID |
DIB015059
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| Drug Name |
Levomequitazine
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| Synonyms |
V-0114; V-0114CP
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| Drug Type |
Small molecular drug
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| Indication | Seasonal allergic rhinitis [ICD-11: CA08.01; ICD-10: J30.2] | Phase 3 | [1] | |
| Company |
Pierre Fabre SA
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H22N2S
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| Canonical SMILES |
C1CN2CCC1C(C2)CN3C4=CC=CC=C4SC5=CC=CC=C53
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| InChI |
1S/C20H22N2S/c1-3-7-19-17(5-1)22(18-6-2-4-8-20(18)23-19)14-16-13-21-11-9-15(16)10-12-21/h1-8,15-16H,9-14H2/t16-/m0/s1
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| InChIKey |
HOKDBMAJZXIPGC-INIZCTEOSA-N
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| CAS Number |
CAS 88598-74-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine receptor (HR) | Target Info | Antagonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034359) | |||
| REF 2 | Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes. J Pharmacol Exp Ther. 1998 Feb;284(2):437-42. | |||
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