Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0KH9W
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| Former ID |
DIB018488
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| Drug Name |
15S-HPETE
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| Synonyms |
15(S)-HPETE; 15-(S)-hydroperoxyeicosatetraenoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C20H32O4
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| Canonical SMILES |
CCCCCC(C=CC=CCC=CCC=CCCCC(=O)O)OO
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| InChI |
1S/C20H32O4/c1-2-3-13-16-19(24-23)17-14-11-9-7-5-4-6-8-10-12-15-18-20(21)22/h4-5,8-11,14,17,19,23H,2-3,6-7,12-13,15-16,18H2,1H3,(H,21,22)/b5-4-,10-8-,11-9-,17-14+/t19-/m0/s1
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| InChIKey |
BFWYTORDSFIVKP-VAEKSGALSA-N
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| CAS Number |
CAS 70981-96-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
8250, 4266120, 8143291, 8616432, 15746930, 26754761, 26754762, 39289882, 47736202, 48034828, 50110772, 57357917, 80686530, 92309755, 99300669, 99302187, 103935525, 104046399, 113854191, 126525052, 131273761, 135651379, 142970237, 162228278, 164757202, 179205525, 230269041, 250132993, 252371187, 252455479, 252464240
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| ChEBI ID |
CHEBI:15628
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Activator | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2482). | |||
| REF 2 | Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc Natl Acad Sci U S A. 2000 May 23;97(11):6155-60. | |||
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