Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0KG1T
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| Drug Name |
Pyrimido-indole derivative 2
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| Synonyms |
PMID26924192-Compound-81
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| Drug Type |
Small molecular drug
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| Company |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H29N7O2
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| Canonical SMILES |
CCN1C(=C2CCCCC2=N1)NC3=NC(=NC4=C3C5=CC(=C(C=C5N4)C6=C(ON=C6C)C)OC)C
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| InChI |
1S/C26H29N7O2/c1-6-33-26(16-9-7-8-10-19(16)31-33)30-25-23-17-12-21(34-5)18(22-13(2)32-35-14(22)3)11-20(17)29-24(23)27-15(4)28-25/h11-12H,6-10H2,1-5H3,(H2,27,28,29,30)
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| InChIKey |
PKOGGTPBCXRZNX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bromodomain and extraterminal domain protein (BET) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Bromodomain and extraterminal domain protein (BET) | Target's Patent Info | [1] | |
| KEGG Pathway | SNARE interactions in vesicular transport | |||
| Reactome | COPII (Coat Protein 2) Mediated Vesicle Transport | |||
| WikiPathways | miR-targeted genes in squamous cell - TarBase | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | BET inhibitors in cancer therapeutics: a patent review.Expert Opin Ther Pat. 2016;26(4):505-22. | |||
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