Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K8MP
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| Former ID |
DAP001235
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| Drug Name |
Permethrin
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| Synonyms |
Ambush; PerFoam; Transpermethrin; Acticin Cream; Elimite Cream; Nix Cream Rinse; Transpermethrin [ISO];FMC 35171; NRDC 146; NRDC 148; PS758_SUPELCO; Permethrin (isomers); Permethrin (isomers) solution; Permethrine,c&t; Trans-(+-)-Permethrin; [3-(phenyloxy)phenyl]methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate; (+)-CIS-PERMETHRIN; (+)-trans-Permethrin; (+-)-cis-Fmc 33297; (+-)-cis-Permethrin; (+-)-trans-Permethrin; (3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate; (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate; 1RS,cis-Permethrin; 1RS-trans-Permethrin; 3-Phenoxybenzyle (1RS)-cis, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylate; 3-phenoxybenzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
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| Drug Type |
Small molecular drug
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| Indication | Sarcoptes scabiei infection [ICD-11: 1G04; ICD-10: B86; ICD-9: 133] | Approved | [1], [2] | |
| Therapeutic Class |
Insecticides
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| Structure |
 |
Download2D MOL |
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| Formula |
C21H20Cl2O3
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| Canonical SMILES |
CC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C
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| InChI |
1S/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3
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| InChIKey |
RLLPVAHGXHCWKJ-UHFFFAOYSA-N
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| CAS Number |
CAS 52645-53-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5646900, 8176555, 10525033, 10525292, 10526594, 14854178, 17395388, 24868001, 24869115, 24869349, 24871630, 24899290, 26675675, 26754479, 26754481, 26754482, 26754483, 26754484, 29215320, 29215321, 34706112, 46505374, 47207113, 48415484, 48421679, 48425983, 49833360, 49959692, 49959696, 50109850, 56310674, 56312325, 56314259, 57260102, 57260103, 57288423, 57312421, 57650455, 57650562, 74717839, 85088539, 85189547, 91696064, 103559256, 104334065, 117452446, 118783839, 121362319, 124800250, 124892140
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| ChEBI ID |
CHEBI:34911
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| ADReCS Drug ID | BADD_D01742 | |||
| SuperDrug ATC ID |
P03AC04
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| SuperDrug CAS ID |
cas=052645531
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Blocker | [3] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074806. | |||
| REF 3 | In vitro assays for repellents and deterrents for ticks: differing effects of products when tested with attractant or arrestment stimuli. Med Vet Entomol. 2003 Dec;17(4):370-8. | |||
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