Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K6CM
|
|||
| Drug Name |
PMID29338548-Compound-16
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
F. HOFFMANN-LA ROCHE AG KOLCZEWSKI, Sabine PINARD, Emmanuel
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C25H29F3N2O2S
|
|||
| Canonical SMILES |
COC1=C(C(=CC(=C1)C(F)(F)F)SC)C(=O)NC2(CCCN3C2CCCC3)C4=CC=CC=C4
|
|||
| InChI |
1S/C25H29F3N2O2S/c1-32-19-15-18(25(26,27)28)16-20(33-2)22(19)23(31)29-24(17-9-4-3-5-10-17)12-8-14-30-13-7-6-11-21(24)30/h3-5,9-10,15-16,21H,6-8,11-14H2,1-2H3,(H,29,31)/t21-,24+/m1/s1
|
|||
| InChIKey |
VEQWRPXCFYIVLR-QPPBQGQZSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glycine transporter GlyT-1 (SLC6A9) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Glycine transporter GlyT-1 (SLC6A9) | Target's Patent Info | [1] | |
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | NRF2 pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Glycine transporter-1 inhibitors: a patent review (2011-2016).Expert Opin Ther Pat. 2018 Mar;28(3):197-210. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.