Drug Information
Drug General Information | Top | |||
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Drug ID |
D0K5JA
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Former ID |
DNC005095
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Drug Name |
8-Cyclohexyloxy-quinolin-2-ylamine
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Synonyms |
CHEMBL185235; 8-Cyclohexyloxy-quinolin-2-ylamine; SCHEMBL5883787
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C15H18N2O
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Canonical SMILES |
C1CCC(CC1)OC2=CC=CC3=C2N=C(C=C3)N
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InChI |
1S/C15H18N2O/c16-14-10-9-11-5-4-8-13(15(11)17-14)18-12-6-2-1-3-7-12/h4-5,8-10,12H,1-3,6-7H2,(H2,16,17)
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InChIKey |
MPHNEJNPZMBSBN-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Peptide ligand-binding receptors | |||
G alpha (q) signalling events | ||||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7. |
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