Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K3LO
|
|||
| Former ID |
DNCL003322
|
|||
| Drug Name |
Romosozumab
|
|||
| Synonyms |
AMG 785
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|
|||
| Drug Type |
Antibody
|
|||
| Indication | Postmenopausal osteoporosis [ICD-11: FB83.11; ICD-10: M81.0; ICD-9: 733] | Approved | [1] | |
| Company |
Amgen
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sclerostin (SOST) | Target Info | . | [1] |
| KEGG Pathway | Wnt signaling pathway | |||
| NetPath Pathway | TWEAK Signaling Pathway | |||
| Reactome | TCF dependent signaling in response to WNT | |||
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019 | |||
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