Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K2SE
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| Former ID |
DNC004489
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| Drug Name |
5-Imidazol-1-yl-5,6,7,8-tetrahydro-quinoline
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| Synonyms |
Quinoline, 5,6,7,8-tetrahydro-5-(1H-imidazol-1-yl)-; 273930-06-6; tetrahydroquinoline 40; CHEMBL52509; BDBM10023; 5-(Imidazol-1-yl)-5,6,7,8-tetrahydroquinoline; 5-(1H-imidazol-1-yl)-5,6,7,8-tetrahydroquinoline
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H13N3
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| Canonical SMILES |
C1CC(C2=C(C1)N=CC=C2)N3C=CN=C3
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| InChI |
1S/C12H13N3/c1-4-11-10(3-2-6-14-11)12(5-1)15-8-7-13-9-15/h2-3,6-9,12H,1,4-5H2
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| InChIKey |
QFNKKYLTOSVDJG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thromboxane-A synthase (TBXAS1) | Target Info | Inhibitor | [1] |
| BioCyc | C20 prostanoid biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Platelet activation | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Arachidonic acid metabolism | ||||
| Phase 1 - Functionalization of compounds | ||||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthas... J Med Chem. 2000 May 4;43(9):1841-51. | |||
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